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Updated: Dec 9, 2025

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
Published on: August 18, 2020
[Clinical variants of psychoses in patients using synthetic cannabinoids (Spice)]
M A Vinnikova1,2, V Yu Skryabin1
1Moscow Research and Practical Centre of Addictions, Moscow, Russia.
Objective:
To describe the structure of psychoses developed due to synthetic cannabinoids (Spice).
Material And Methods:
Forty-six men, aged 18-35 years, with psychosis during abstinence were studied and followed up for 2 years.
Results And Conclusion:
Four clinical variants with predominant delirious symptoms (27%) or hallucinatory symptoms (19%) or affective-delusions (21%) or mental automatisms (33%) were identified. The follow-up revealed the manifestations of schizophrenic process in 17% of the patients. Clinical and differential diagnostic characteristics of these variants in synthetic cannabinoids users are described.
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