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Updated: Dec 9, 2025

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
[Complex treatment of a patient with neurofibromatosis type 2]
A Yu Rynda1, V E Olyushin1, D M Rostovtsev1
1Polenov Russian Research Neurosurgical Institute of Almazov National Medical Research Center of the Ministry of Health of Russia, St. Petersburg, Russia.
Abstract:
Neurofibromatosis type 2, a rare disease, the most characteristic manifestation of which is the presence of bilateral vestibular schwannomas, less often schwannomas of other cranial, spinal and peripheral nerves. Much less frequent are meningiomas (intracranial, including meningiomas of the optic nerves, and spinal), epindymomas and gliomas. As a rule, in one patient several formations occur simultaneously, which creates a certain difficulty in treatment tactics. The authors present a case of type 2 neurofibromatosis in a 22-year-old female patient with multiple schwannomas of spinal roots and an atypical intraventricular meningioma.
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