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Updated: Dec 9, 2025

Specific Labeling of Mitochondrial Nucleoids for Time-lapse Structured Illumination Microscopy
Published on: June 4, 2020
One-step synthesis of mitochondrion-targeted fluorescent carbon dots and fluorescence detection of silver ions
Yue Hou1, Hanxiao Liu1, Zhanxian Li1
1Green Catalysis Center and College of Chemistry, Zhengzhou University, Zhengzhou, 450001, China. lizx@zzu.edu.cn yumm@zzu.edu.cn.
Abstract:
Silver ions (Ag+) are the most representative harmful ions found in polluted water and widely used in many industries; excessive ingestion of Ag+ in the human body may result in interaction with different metabolites in the human body and in aquatic microorganisms, leading to many diseases. Therefore, there is a great desire to develop good fluorescent probes for Ag+. Herein, a kind of mitochondrion-targeted fluorescent carbon dot was developed. These carbon dots exhibit 29.5% fluorescence quantum yield in water, good photostability and thermal stability. The as-fabricated carbon dots can quickly detect Ag+ in 100% water solution with good selectivity and anti-interference ability. Further, the carbon dots have been successfully applied to monitor Ag+ in living cells via the dual-channel method.

