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Related Experiment Video

Updated: Dec 9, 2025

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Aging Modulates Prefrontal Plasticity Induced by Executive Control Training.

Hugo Najberg¹, Laura Wachtl¹, Marco Anziano¹

¹Neurology Unit, Medicine Section, Faculty of Science and Medicine, University of Fribourg, 1700, Fribourg, Switzerland.

Cerebral Cortex (New York, N.Y. : 1991)

|September 15, 2020

Summary

Older adults can improve inhibitory control through training, enhancing brain efficiency. However, the specific brain mechanisms involved differ compared to younger adults, highlighting age-related plasticity.

Keywords:

ERP aging inhibitory control plasticity training

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Area of Science:

Neuroscience
Cognitive Psychology
Gerontology

Background:

Inhibitory control, crucial for cognitive function, typically declines with age.
The potential for training to enhance inhibitory control in older adults is not well understood.
Understanding age-related changes in neurocognitive processes is vital for healthy aging research.

Purpose of the Study:

To investigate the effects of inhibitory control training (ICT) on behavior and neuroimaging activity in older adults.
To compare the plasticity of inhibitory control in older adults versus young adults.
To examine how aging influences the brain mechanisms underlying inhibitory control plasticity.

Main Methods:

A randomized controlled trial using adaptive gamified Go/NoGo inhibitory control training (ICT).
Behavioral assessments of performance, impulsivity traits, and quality of life.
Electrical neuroimaging, specifically analyzing P3 and N2 event-related potentials components.
Comparison between ICT, working-memory training, and age groups (older vs. young adults).

Main Results:

ICT led to performance improvements in older adults, but increased impulsivity and did not generalize to traits or quality of life.
Older adults showed a quantitative reduction in prefrontal network activity during the P3 component after ICT.
ICT induced distinct configurational changes in the medial-frontal network (N2 component) in older adults compared to young adults.

Conclusions:

Older adults demonstrate preserved capacity for training-induced plasticity in executive control.
Aging interacts with brain mechanisms underlying inhibitory control plasticity.
While ICT enhances inhibitory efficiency in older adults, the neural processing differs from that in younger individuals.