Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

iPS Cell Differentiation

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.

Induced Pluripotent Stem Cells

Induced Pluripotent Stem Cells

Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Toward a PSMA PET-mpMRI pathway for biopsy decision-making in men with suspected prostate cancer: interim results from the prospective BIOPSTAGE trial.

Frontiers in oncology·2026

Same author

How Regulation 536/2014 Is Changing Academic Research with Therapeutic Radiopharmaceuticals: A Local Experience.

Pharmaceuticals (Basel, Switzerland)·2025

Same author

Efficacy, toxicity, and clinical outcomes of 177Lu-PSMA-617 radioligand therapy at 5.5 GBq per cycle in patients with advanced castration-resistant prostate cancer: a prospective, single arm, phase II study.

European journal of nuclear medicine and molecular imaging·2025

Same author

Production and Quality Control of [<sup>68</sup>Ga]Ga-FAPI-46: Development of an Investigational Medicinal Product Dossier for a Bicentric Clinical Trial.

Pharmaceuticals (Basel, Switzerland)·2025

Same author

From Biological Waste to Therapeutic Resources: A Comprehensive Review of Stem Cell Sources, Characterization, and Biomedical Potentials.

Stem cell reviews and reports·2025

Same author

Hyaluronic Acid-Decorated Liposomes for the Intrapulmonary Delivery of Imatinib: A Targeted Treatment for Postinflammatory Pulmonary Fibrosis.

Small science·2025

Search research articles

Related Experiment Video

Updated: Dec 9, 2025

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

Stem Cells and Therapy: Emerging Approaches.

Manuela Monti¹

¹Biotechnology laboratories, Research Center for Regenerative Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia. M.Monti@smatteo.pv.it.

European Journal of Histochemistry : EJH

|September 15, 2020

Summary

This volume explores stem cell biology applications in translational medicine. It provides clear explanations, illustrations, and practical tips for reproducible research results.

Area of Science:

Stem Cell Biology
Translational Medicine

Background:

Stem cells hold significant promise for regenerative medicine and disease treatment.
Translational medicine aims to bridge the gap between laboratory discoveries and clinical applications.

Purpose of the Study:

To elucidate the potential of stem cell biology in advancing translational medicine.
To provide practical guidance for achieving reproducible results in stem cell research.

Main Methods:

The content is presented across ten chapters.
Includes clear explanations and color illustrations.
Offers practical tips and suggestions for experimental reproducibility.

Main Results:

Demonstrates the utility of stem cell biology in translational medicine.

More Related Videos

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

Related Experiment Videos

Last Updated: Dec 9, 2025

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

High Throughput Characterization of Adult Stem Cells Engineered for Delivery of Therapeutic Factors for Neuroprotective Strategies

Published on: January 4, 2015

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Cortical Neurogenesis: Transitioning from Advances in the Laboratory to Cell-Based Therapies

Published on: July 19, 2007

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

Highlights methods for obtaining reliable and reproducible experimental outcomes.

Conclusions:

Stem cell biology offers powerful tools for translational medicine.
Reproducible results are achievable through careful methodology and practical guidance.