Search research articles

Search research articles

Related Experiment Videos

[Invasive pulmonary aspergillosis].

C H Marquette¹, B Wallaert, P Ramon

¹Service de Pneumologie et Immuno-allergologie, Hôpital A. Calmette, Lille.

Revue Des Maladies Respiratoires

|January 1, 1988

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

From parasites to allergy: a second receptor for IgE.

Immunology today·2014

Same author

[Hypersensitivity pneumonitis in a chicory worker].

Revue des maladies respiratoires·2008

Same author

Keratinocyte growth factor improves alterations of lung permeability and bronchial epithelium in allergic rats.

The European respiratory journal·2007

Same author

[Characteristics of mild asthma: clinical signs and medication use. Position statement of the Mild Asthma Working Group (174)].

Revue des maladies respiratoires·2007

Same author

High erythropoietin and low vascular endothelial growth factor levels in cerebrospinal fluid from hypoxemic ALS patients suggest an abnormal response to hypoxia.

Neuromuscular disorders : NMD·2006

Same author

[Characteristics of mild asthma: descriptive epidemiology and nature of bronchial inflammation. Position of the Mild Asthma Working Group].

Revue des maladies respiratoires·2006

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Invasive pulmonary aspergillosis, a fungal pneumonia, often affects immunocompromised patients. Early diagnosis via broncho-alveolar lavage improves prognosis for this antibiotic-resistant infection.

Area of Science:

Medical Mycology
Infectious Diseases
Pulmonology

Context:

Invasive pulmonary aspergillosis (IPA) is a severe opportunistic infection.
Common in immunocompromised individuals, particularly those with prolonged leucopaenia, cytotoxic drugs, or steroid therapy.
Aspergillus fumigatus proliferation occurs due to impaired immune defenses.

Purpose:

To describe the clinical presentation, diagnosis, and treatment of IPA.
To highlight the diagnostic utility of broncho-alveolar lavage (BAL).
To emphasize the link between diagnostic speed and patient prognosis.

Summary:

IPA presents as acute febrile pneumonia, often resistant to antibiotics.
Radiological findings include nodules, bilateral infiltrates, and cavitation.

Related Experiment Videos

Broncho-alveolar lavage is a valuable non-invasive diagnostic tool for detecting Aspergillus.

Sputum analysis has limited sensitivity and specificity.

Impact:

Early diagnosis, especially with BAL, is crucial for improving patient outcomes in IPA.
Highlights the limitations of traditional diagnostic methods like sputum examination.
Informs clinical practice regarding the management of opportunistic fungal pneumonias.