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Incidence and case fatality rate of COVID-19 in patients with inflammatory articular diseases

Natalia Mena Vázquez1, Sara Manrique-Arija2, Pablo Cabezudo-García3

  • 1UGC de Reumatología, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Regional Universitario de Málaga, Universidad de Málaga, Málaga, Spain.

International Journal of Clinical Practice
|September 15, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) incidence and fatality rates are not elevated in patients with inflammatory articular diseases (IAD). Older age was identified as a significant risk factor for COVID-19 fatality in this population.

Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Epidemiology

Background:

  • Inflammatory articular diseases (IAD) encompass conditions like rheumatoid arthritis, psoriatic arthritis, and axial spondyloarthritis.
  • Understanding the impact of coronavirus disease 2019 (COVID-19) on IAD patients is crucial for clinical management.
  • Previous studies have not clearly defined COVID-19 outcomes in IAD populations.

Purpose of the Study:

  • To determine the incidence and fatality rates of COVID-19 among patients with IAD.
  • To identify specific risk factors associated with COVID-19 fatality in IAD patients.

Main Methods:

  • A cross-sectional observational study comparing IAD patients with COVID-19 to matched controls.
  • Cumulative incidence (CI) and case fatality rate (CFR) were primary outcomes.
  • Multiple logistic regression analysis was used to identify fatality risk factors in IAD patients.

Main Results:

  • No significant differences in COVID-19 CI or CFR were observed between IAD patients and controls.
  • However, COVID-19 CI was higher in psoriatic arthritis and axial spondyloarthritis patients.
  • Older age was the primary risk factor for fatality in IAD patients with COVID-19.

Conclusions:

  • COVID-19 incidence, fatality rates, and disease characteristics do not appear to be increased in patients with IAD.
  • Older age is a significant risk factor for COVID-19-related fatality in the IAD cohort.
Abstract

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