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Updated: Dec 9, 2025

06:12
Imaging Dpp Release from a Drosophila Wing Disc
Published on: October 30, 2019
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Dally-like Is Unlike Dally in Assisting Wingless Spread
1Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Waldeyerstrasse 15, 48149 Münster, Germany.
Developmental Cell
|September 15, 2020
Abstract:
Lipidated morphogens can spread within tissues to regulate cell fate during development or tissue repair. How these insoluble molecules reach distant target cells remains unclear. Reporting in Nature, McGough et al. (2020) reveal the secret of how the cell-surface proteoglycan Dally-like-protein (Dlp) promotes long-range signaling of the palmitoylated morphogen Wingless.
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