Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

A game-theoretic approach to donor kidney sharing.

¹Brunel University, Uxbridge, Middlesex, England.

Social Science & Medicine (1982)

|January 1, 1988

Summary

Kidney transplant graft survival depends on human leukocyte antigen (HLA) matching. Game theory predicts that kidney sharing between transplant centers may lead to non-cooperation and lower survival rates without policy interventions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Performance of pile-up mitigation techniques for jets in [Formula: see text] collisions at [Formula: see text] TeV using the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

Probing lepton flavour violation via neutrinoless [Formula: see text] decays with the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

A new method to distinguish hadronically decaying boosted <i>Z</i> bosons from <i>W</i> bosons using the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

Measurement of the differential cross-sections of prompt and non-prompt production of [Formula: see text] and [Formula: see text] in <i>pp</i> collisions at [Formula: see text] and 8 TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

Measurement of the centrality dependence of the charged-particle pseudorapidity distribution in proton-lead collisions at [Formula: see text] TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

Search for new phenomena in events with at least three photons collected in <i>pp</i> collisions at [Formula: see text] = 8 TeV with the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Area of Science:

Nephrology
Transplantation immunology
Game theory

Background:

Graft survival in renal transplantation is significantly influenced by human leukocyte antigen (HLA) tissue matching between donor and recipient.
Geographical separation of transplant centers can lead to missed opportunities for optimal donor-recipient matching through kidney exchange.

Purpose of the Study:

To analyze the strategic decisions of transplant centers regarding offering and exchanging donor kidneys.
To evaluate the impact of these decisions on overall graft survival rates using a game-theoretic framework.

Main Methods:

A game-theoretic model was developed to represent the strategic interactions between transplant centers.
The model analyzed the choice to "offer or not" a donor kidney, considering the uncertainty of reciprocation.

Main Results:

The equilibrium analysis predicts a tendency towards non-cooperation among transplant centers.
This non-cooperative strategy is likely to result in collectively sub-optimal renal allograft survival rates.

Conclusions:

Without effective policy interventions, strategic non-cooperation in kidney exchange can hinder optimal graft survival.
Policy options such as exchange incentives and coercive measures are suggested to improve cooperation and enhance transplant outcomes.

Related Experiment Videos