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Measurement of Maximum Isometric Force Generated by Permeabilized Skeletal Muscle Fibers
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    Area of Science:

    • Materials Science
    • Optical Engineering
    • Biomedical Engineering

    Background:

    • Miniaturized sensors are crucial for precise measurements in confined spaces.
    • Fiber optic sensors offer advantages in biocompatibility and electromagnetic immunity.
    • Fabry-Perot interferometry provides a robust platform for sensing applications.

    Purpose of the Study:

    • To present a novel miniature all-fiber Fabry-Perot sensor for force measurement.
    • To demonstrate the sensor's capability for high-resolution force detection.
    • To explore its application in measuring surface tension and examining biological samples.

    Main Methods:

    • Fabrication of a thin silica diaphragm at the fiber tip.
    • Integration of a silica pole and sensing probe for force application.
    • Experimental characterization of the sensor's force sensing resolution and range.

    Main Results:

    • Demonstrated a force sensing resolution of approximately 0.6 µN.
    • Achieved an unambiguous sensor measurement range of approximately 0.6 mN.
    • Successfully applied the sensor for surface tension measurements and biological sample examination.

    Conclusions:

    • The developed miniature all-fiber Fabry-Perot sensor is effective for precise force measurement.
    • Its high resolution and compact size make it suitable for delicate applications.
    • The sensor shows promise for advanced surface tension analysis and biomedical diagnostics.