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Published on: August 17, 2022
Population data for 20 insertion-null allele markers in the Li ethnic minority from Hainan Province
Jie Xu1, Lijuan Sun2, Xianwen Wang1
1Criminal Technology Detachment of Haikou Public Security Bureau, Haikou, China.
Abstract:
Insertion/null polymorphisms (INNULs) can be used as an alternative marker of STRs to detect the highly degraded samples in forensic cases. In this study, we evaluated the genetic data of 20 INNUL markers in the Innotyper® 21 Human DNA Analysis Kit (InnoGenomics) for Hainan Li population, including allele frequencies and forensic parameters. No significant deviation from Hardy-Weinberg equilibrium and linkage disequilibrium was found in all loci after Bonferroni correction. The combined power of discrimination (CPD) was 0.99999891, the combined power of exclusion for duo paternity testing (CPEduo) was 0.75274389, and the combined power of exclusion for trio paternity testing (CPEtrio) was 0.94766143. These data would be useful for the application of the kit in practice and the research of the kit used in molecular anthropology studies.
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