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Food allergy diagnosis protocol.

C Ortolani1, E Pastorello, M Ispano

  • 1Ospedale Nigarda Cà Granda, Divisione Bizzozero, Milano, Italy.

Allergie Et Immunologie
|February 1, 1988
PubMed
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This study outlines diagnostic protocols for recurrent and chronic symptoms, identifying causative foods through allergy testing and dietary challenges. It confirms the reliability of PRICK and RAST tests in diagnosing food allergies.

Area of Science:

  • Clinical immunology
  • Gastroenterology
  • Allergy diagnostics

Background:

  • Recurrent and chronic symptoms often necessitate accurate diagnosis of underlying causes.
  • Differentiating between food allergy and food intolerance is crucial for effective management.
  • Established diagnostic methods require validation for reliability and efficacy.

Purpose of the Study:

  • To propose a definitive diagnostic protocol for recurrent or chronic symptoms related to food.
  • To evaluate the reliability of PRICK, RAST, and food provocation tests.
  • To differentiate between food allergy and food intolerance using a structured approach.

Main Methods:

  • For recurrent symptoms: PRICK testing, Radioallergosorbent Test (RAST), and food provocation tests were employed.

Related Experiment Videos

  • For chronic symptoms: A non-allergenic diet followed by systematic re-introduction of foods was used.
  • Diagnostic accuracy was assessed on 100 patients for PRICK/RAST and 386 cases for dietary challenges.

    • Main Results:

    • The reliability of PRICK and RAST tests was demonstrated in 100 patients.
    • Dietary elimination and re-introduction successfully identified causative foods in 386 cases of urticaria and angio-oedema.
    • Food-linked reactions were identified as the origin in 1.9% of these cases.

    Conclusions:

    • The proposed protocol effectively diagnoses food-related recurrent and chronic symptoms.
    • PRICK and RAST tests are reliable diagnostic tools for food allergies.
    • Distinguishing food allergy from intolerance is achievable through careful dietary management and observation.