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A bifunctional fluorescent sensor for CCCP-induced cancer cell apoptosis imaging
Huawei Niu1, Yongru Zhang, Jun Tang
1Green Catalysis Center, College of Chemistry, Zhengzhou University, Zhengzhou 450001, P. R. China. yeyong03@tsinghua.org.cn.
Abstract:
The detailed mechanism and the extent of pH/SO2 changes during apoptosis remain unknown. The developed sensor NPCF for SO2 and pH dual detection illustrates that SO2 can reduce the inflammation caused by LPS and the acidification of the environment. The levels of SO2 and pH change during carbonyl cyanide m-chlorophenylhydrazone (CCCP)-induced apoptosis.
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