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Trajectory Data Analyses for Pedestrian Space-time Activity Study
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AZTEK: Adaptive zero TE k-space trajectories.

Tanguy Boucneau1, Brice Fernandez2, Florent L Besson1,3

  • 1Université Paris-Saclay, CEA, CNRS, Inserm, BioMaps, Orsay, France.

Magnetic Resonance in Medicine
|September 16, 2020
PubMed
Summary
This summary is machine-generated.

Adaptive ZTE k-space trajectories (AZTEK) improve 3D lung MRI by reducing motion artifacts. This new method enhances image quality for dynamic imaging, making details clearer in the lungs.

Keywords:
ZTElungmotionradialtrajectory

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Area of Science:

  • Magnetic Resonance Imaging
  • Medical Physics
  • Radiology

Background:

  • 3D lung MRI is challenging due to short signal lifetimes and respiratory motion.
  • Standard Zero-TE (ZTE) pulse sequences address short T2* but have k-space trajectories unsuitable for motion correction.
  • Retrospective gating and motion correction are difficult with continuous readout gradients in ZTE.

Purpose of the Study:

  • To develop and evaluate adaptive ZTE k-space trajectories (AZTEK) for improved 3D lung MRI.
  • To adapt ZTE acquisition for moving organs, enabling retrospective gating and motion correction.
  • To maintain seamless transitions between spokes for ZTE compatibility.

Main Methods:

  • Proposed AZTEK, a set of 3D radial trajectories with three tuning parameters.
  • Compared standard ZTE and AZTEK trajectories using static and moving phantoms.
  • Evaluated trajectories in thoracic imaging of three human volunteers (1 healthy, 2 lung cancer patients).

Main Results:

  • Comparable image quality between standard and AZTEK trajectories in static phantoms.
  • AZTEK alleviated undersampling artifacts in moving phantom images compared to standard ZTE.
  • Improved image quality and delineation of lung details observed in human subjects using AZTEK.

Conclusions:

  • AZTEK enables 3D dynamic ZTE lung imaging with retrospective gating.
  • The technique uniformly samples k-space for arbitrary respiratory motion gates.
  • AZTEK preserves static image quality, enhances dynamic image quality, and is compatible with ZTE.