Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.6K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.6K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

2.2K
The pathophysiology of pneumonia involves the following steps:
2.2K
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

3.8K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
3.8K
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

3.9K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
3.9K
Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

460
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
460
Infertility in Males01:23

Infertility in Males

453
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
453

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prompt Framing and Evidence Requirements for AI-Generated Educational Responses in Dental Education: An Experimental Study.

JMIR medical education·2026
Same author

Mapping the Evidence on Oral Health Interventions and Cognitive Status in Alzheimer's Disease: A Scoping Review.

Brain sciences·2026
Same author

Condition-Specific Healthcare Expenditures for Treated Knee Injuries and Shoulder Disorders in the Post-Pandemic United States.

Healthcare (Basel, Switzerland)·2026
Same author

Frailty and Sarcopenia as Predictors of Functional Recovery After Total Hip and Knee Arthroplasty: A Narrative Review.

Journal of clinical medicine·2026
Same author

Longitudinal Psychometric Properties of the Myotonic Dystrophy Health Index in a Large Multicenter Cohort of People Living With Myotonic Dystrophy Type 1.

Muscle & nerve·2026
Same author

Artificial Intelligence in Dental and Orthopedic Skeletal Imaging: A Scoping Review of Methodological Convergence and Translational Gaps.

Journal of imaging informatics in medicine·2026

Related Experiment Video

Updated: Dec 8, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.6K

Men and COVID-19: A Pathophysiologic Review.

Martin S Lipsky1,2, Man Hung1,3,4,5

  • 1Roseman University of Health Sciences College of Dental Medicine, South Jordan, UT, USA.

American Journal of Men'S Health
|September 16, 2020
PubMed
Summary

Men experience more severe COVID-19 and higher mortality than women. This review explores biological and behavioral factors, like immune response and hormones, that may explain these sex differences in coronavirus disease 2019 outcomes.

Keywords:
COVID-19MenSAR-CoV-2coronaviruscrisispandemicpathologypublic health

More Related Videos

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.7K
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

Published on: September 22, 2023

1.9K

Related Experiment Videos

Last Updated: Dec 8, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.6K
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.7K
Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
09:02

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions

Published on: September 22, 2023

1.9K

Area of Science:

  • Virology and Epidemiology
  • Sex-Based Health Disparities

Background:

  • Coronaviruses, including SARS-CoV-2 causing COVID-19, present a global health challenge.
  • Epidemiological data indicate a higher incidence of severe disease and mortality in men compared to women with COVID-19.
  • Understanding these sex-based differences is crucial for effective public health strategies.

Purpose of the Study:

  • To review and analyze the factors contributing to increased COVID-19 severity and mortality in men.
  • To explore potential biological and behavioral explanations for observed sex-based disparities in COVID-19 outcomes.

Main Methods:

  • Literature review examining existing epidemiological data on COVID-19 sex differences.
  • Analysis of laboratory and animal studies investigating sex-related responses to SARS-CoV-2 infection.
  • Exploration of proposed mechanisms including ACE2 receptors, immune function, hormones, habits, and coinfections.

Main Results:

  • Evidence suggests sex-related differences in physiological and behavioral factors influence COVID-19 outcomes.
  • Potential contributing factors include variations in angiotensin-converting enzyme 2 receptor expression, immune responses, hormonal profiles, lifestyle habits, and coinfection rates between sexes.
  • These factors collectively offer plausible explanations for why men exhibit greater disease severity and mortality.

Conclusions:

  • Sex-based differences significantly impact the clinical presentation and outcomes of COVID-19.
  • Further research into these disparities can inform the development of targeted treatments and public health policies.
  • Implementing early recognition and aggressive testing in at-risk male populations may improve management of coronavirus disease 2019.