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Updated: Dec 8, 2025

Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
A Review of Cyclodestructive Procedures for the Treatment of Glaucoma
Nandita Anand1, Emma Klug1, Abraham Nirappel1
1Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School , Boston, MA, USA.
Abstract:
Cyclodestruction aims to reduce aqueous humor production through the coagulation or destruction of the ciliary body and has been an important treatment choice for glaucoma since the 1930s. The purpose of the current review is to highlight the evidence regarding the safety and efficacy of various cyclodestructive modalities, emphasizing peer-reviewed articles from the last 20 years and the most common variants of these procedures. The review focuses primarily on the two most common variants of transscleral cyclophotocoagulation (TS-CPC), continuous-wave diode cyclophotocoagulation (CW-TSCPC) and MicroPulse diode cyclophotocoagulation (MP-TSCPC) as well as endoscopic cyclophotocoagulation (ECP) and high-intensity focused ultrasound cyclodestruction (HIFU). We believe that the role of cyclodestruction in glaucoma treatment will only continue to expand given the advances in the field, particular with regards to targeted ciliary body destruction and improvement in the safety profile.
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