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Two further cases of acute myeloid leukemia with trisomy 4
C F Hoyle1, B J Boughton, F G Hayhoe
1Department of Haematological Medicine, University Clinical School, Cambridge, England.
Cancer Genetics and Cytogenetics
|August 1, 1988
Abstract:
Two cases of acute myeloid leukemia (FAB M1 and M2) with trisomy 4 are described. Morphologic abnormalities were confined to the granulocytic monocytic lineage with no evidence of erythroid or megakaryocytic involvement. One of the cases, who also had trisomy 13, presented initially with skin infiltration without bone marrow involvement.