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Behavioral Differences in the Preference for Hepatitis B Virus Vaccination: A Discrete Choice Experiment
Na Guo1, Jian Wang2,3, Stephen Nicholas4,5,6,7
1China Population and Development Research Center, Beijing 100081, China.
Vaccines
|September 17, 2020
Summary
Understanding preferences for hepatitis B virus (HBV) vaccination is key to increasing uptake. Adults prioritized high protection rates and long duration, with behavioral factors influencing choices.
Area of Science:
- Public Health
- Behavioral Economics
- Vaccinology
Background:
- Vaccine uptake is influenced by individual preferences and behavioral factors.
- Understanding these preferences is crucial for designing effective public health interventions.
- Hepatitis B virus (HBV) vaccination is a critical public health measure.
Purpose of the Study:
- To analyze adult preferences for hepatitis B virus (HBV) vaccination attributes.
- To identify behavioral determinants influencing HBV vaccine choice.
- To inform policy interventions aimed at increasing HBV vaccination rates.
Main Methods:
- A discrete choice experiment (DCE) was conducted with 353 adults in Shandong province, China.
- A mixed logit model was used to estimate preferences for vaccination attributes.
- Attributes included protection rate, duration, side-effect risk, and cost.
Main Results:
- Adults most valued "99% hepatitis B protection," followed by "20 years' protection duration" and a "1 in 150,000 risk of side-effects."
- Lower time discount rates, non-overconfidence, and higher risk aversion were associated with increased likelihood of vaccination.
- Specific behavioral traits correlated with preferences for certain attributes (e.g., risk aversion and side-effect risk).
Conclusions:
- Behavioral factors significantly shape preferences for HBV vaccination attributes.
- Public health interventions should target identified behavioral determinants to enhance vaccine demand.
- Tailoring interventions based on psychological profiles can improve vaccination strategies.

