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Updated: Dec 8, 2025

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Split Hybridization Probe Utilizing a DNA Fluorescent Light-up Aptamer as a Signal Reporter for Sequence-Specific Nucleic Acid Analysis
Published on: July 8, 2025
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A one-step sensitive dynamic light scattering method for detection using split aptamer fragments
Xiaohai Yang1, Jiahao Huang1, Qing Wang1
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Key Laboratory for Bio- Nanotechnology and Molecular Engineering of Hunan Province, Hunan University, Changsha, 410082, China. kmwang@hnu.cn.
Analytical Methods : Advancing Methods and Applications
|September 17, 2020
Abstract:
A one-step sensitive method using dynamic light scattering (DLS) was introduced for direct detection of adenosine with high selectivity. For the first time, DLS was used to detect small molecules directly and quantitatively.

