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Giant Gastric Polyp in Peutz-Jeghers Syndrome: Report of a Case
Divya Murali1, Anjan Kumar Dhua1, Vishesh Jain1
1Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.
Insights
Peutz-Jeghers syndrome (PJS), an inherited disorder, typically causes intestinal polyps and skin spots. This case highlights an extremely rare PJS presentation: a giant adenomatous gastric polyp, crucial for diagnosing atypical cases.
Area of Science:
- Gastroenterology
- Genetics
- Oncology
Background:
- Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder.
- It is characterized by hamartomatous polyps, mucocutaneous pigmentation, and increased cancer risk.
Observation:
- A rare case of PJS presented with a giant adenomatous gastric polyp.
- This contrasts with the typical hamartomatous polyps found in PJS.
Findings:
- The study reports an unusual association between PJS and an adenomatous giant gastric polyp.
- This finding suggests adenomatous polyps can be an atypical manifestation of PJS.
Implications:
- Recognizing this rare presentation is vital for accurate PJS diagnosis.
- Increased awareness can prevent missed diagnoses in patients with atypical PJS features.
Abstract:
Peutz-Jeghers syndrome (PJS) is inherited as an autosomal dominant disorder presenting as hamartomatous polyps in the small bowel, mucocutaneous pigmentation and with a predisposition to develop cancer. We report a case of PJS, with an adenomatous giant gastric polyp. The purpose is to highlight that adenomatous giant gastric polyp may be an extremely rare presentation of PJS. Awareness of this possibility will help us in not missing out these atypical cases of PJS.
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