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Neighborhood context and kidney disease in Philadelphia
Suzanne M Boyle1, Yuzhe Zhao2, Edgar Chou3
1Department of Medicine, Section of Nephrology, Hypertension and Kidney Transplantation, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Lower neighborhood socioeconomic status is linked to higher chronic kidney disease (CKD) risk. Poorer walkability in neighborhoods may also worsen glycemic control for CKD patients.
Area of Science:
- Public Health
- Epidemiology
- Social Determinants of Health
Background:
- Chronic kidney disease (CKD) affects 10% of the U.S. population, posing significant health risks and costs.
- Neighborhood context is increasingly recognized as a potential factor influencing CKD risk and management.
Purpose of the Study:
- To investigate the association between neighborhood context indicators and CKD risk.
- To examine the relationship between neighborhood characteristics and secondary outcomes like glycemic control and blood pressure in CKD patients.
Main Methods:
- Utilized generalized linear equations to analyze data from 23,692 primary care patients in Philadelphia (2016-2017).
- Assessed neighborhood context metrics including socioeconomic status, food access, walkability, social capital, and crime rates.
- Adjusted for individual-level factors such as age, sex, race/ethnicity, and insurance coverage.
Main Results:
- Lower neighborhood socioeconomic index was associated with a significantly higher risk of CKD (aRR 1.46 for lowest vs. highest tertile).
- Among CKD patients, residing in neighborhoods with mid-level walkability was linked to poorer glycemic control (aRR 1.20).
Conclusions:
- Neighborhood socioeconomic status is a significant factor associated with CKD risk.
- Walkability may play a role in glycemic control for individuals with CKD, suggesting potential targets for intervention.
- Further research is needed to understand the mechanisms linking neighborhood walkability to glycemic control.
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