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Updated: Dec 8, 2025
A Preclinical Mouse Model of Osteosarcoma to Define the Extracellular Vesicle-mediated Communication Between Tumor and Mesenchymal Stem Cells
Published on: May 6, 2018
Left ventricular metastasis of osteosarcoma: A report of an unusual case
Nour El Houda Snoussi1, Fatimazohra Radi2,3, Yousra Oussou4
1Department of Cardiology B, IBN SINA Hospital Center, Mohammed V University, Rabat, Morocco.
Background:
Secondary cardiac tumors are far more frequent than primary tumors. Cardiac metastasis of osteosarcoma is extremely rare.
Case Presentation:
We report a 14-year-old child with left femur osteosarcoma that had metastasized to the left ventricle after 30 months of follow-up. The diagnosis was confirmed based on the findings of transthoracic echocardiography and fluorodeoxyglucose positron emission tomography/computed tomography. Surgical removal was indicated in the patient, but his parents refused this decision, and the patient was discharged and admitted to a pediatric oncology center for chemotherapy. The patient died after four courses of chemotherapy.
Conclusion:
Cardiac metastasis of osteosarcoma is a strong predictor of disease. The demographic differences shown in our case include male sex and a short interval between onset and cardiac involvement.
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