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Related Concept Videos

Hydrogen Bonds00:26

Hydrogen Bonds

129.1K
Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared....
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Related Experiment Video

Updated: Dec 8, 2025

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke
09:41

Injection of Hydrogel Biomaterial Scaffolds to The Brain After Stroke

Published on: October 1, 2020

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Molecular Hydrogen Application in Stroke: Bench to Bedside.

Lei Huang1, Cameron Lenahan2, Warren Boling1

  • 1Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354, United States.

Current Pharmaceutical Design
|September 17, 2020
PubMed
Summary
This summary is machine-generated.

Molecular hydrogen shows promise as a new therapy for stroke, a leading cause of death. This review covers its potential benefits and protective effects in stroke patients and models.

Keywords:
Ischemic strokeantioxidanthydrogen gashydrogen-rich salinehydrogen-rich waterintracerebral hemorrhageneuroprotectionsubarachnoid hemorrhage

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Last Updated: Dec 8, 2025

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Area of Science:

  • Neuroscience
  • Medical Gas Therapy
  • Stroke Research

Background:

  • Stroke represents a significant global health burden, leading to high mortality and morbidity.
  • Current therapeutic options for stroke are limited, necessitating the exploration of novel treatments.

Purpose of the Study:

  • To review the existing experimental and clinical evidence on molecular hydrogen therapy for stroke.
  • To discuss the neuroprotective mechanisms underlying molecular hydrogen's effects in stroke.

Main Methods:

  • Literature review of preclinical studies (animal models) and clinical trials involving molecular hydrogen in stroke.
  • Analysis of research investigating the biochemical and cellular pathways affected by molecular hydrogen.

Main Results:

  • Molecular hydrogen demonstrates therapeutic potential in various stroke models.
  • Evidence suggests molecular hydrogen possesses significant neuroprotective properties against stroke-induced damage.

Conclusions:

  • Molecular hydrogen therapy is a promising novel approach for stroke treatment.
  • Further research into molecular hydrogen's neuroprotective mechanisms could lead to improved stroke interventions.