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Synthesis and biological activity of some pyrrole derivatives. I
M T Cocco1, C Congiu, A Maccioni
1Istituto di Chimica Farmaceutica, Tossicologica ed Applicata Università di Cagliari, Italy.
Il Farmaco; Edizione Scientifica
|January 1, 1988
Abstract:
The synthesis of some 5-substituted 2-amino-3-cyano (and 3-carboethoxy)pyrroles is described starting from the cyano- and carboethoxyacetomidines and the alpha-halogeno ketones. The compounds tested in vitro as antimicrobial agents did not show any significative activity.