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Neurobrucellosis: a Case Report with an Unusual Presentation
Mostafa Meshref1, Yara Amro2, Mahmoud Ahmed Ebada3
1Department of Neurology, King Khaled Hospital, Hail. Saudi Arabia.
Recent Patents on Anti-Infective Drug Discovery
|September 18, 2020
Summary
Neurobrucellosis, a severe complication of brucellosis, can present with neurological symptoms. Early diagnosis and occupational history are crucial for effective treatment of this zoonotic infection.
Area of Science:
- Infectious Diseases
- Neurology
- Zoonosis
Background:
- Brucellosis is a zoonotic infection caused by Brucella bacteria.
- Neurobrucellosis is a rare but severe complication of brucellosis, affecting the nervous system.
Observation:
- A farmer presented with fever and confusion, exhibiting signs of meningeal irritation.
- Cerebrospinal fluid analysis revealed decreased glucose and elevated protein levels.
- High-titer antibodies for Brucella abortus and melitensis confirmed the diagnosis.
Findings:
- The patient received two weeks of triple therapy for brucellosis.
- Significant improvement in consciousness was observed post-treatment.
- The patient recovered fully within days.
Implications:
- Highlights the importance of considering neurobrucellosis in patients with unexplained neurological signs.
- Emphasizes the critical role of occupational history in diagnosing zoonotic infections.
- Suggests prompt treatment can lead to rapid recovery from neurobrucellosis.
