Screening Test on Metabolic Syndrome Using Electro Interstitial Scan Instrument.

Area of Science:

• Cardiovascular Health
• Metabolic Disorders
• Diagnostic Technology

Background:

• Metabolic syndrome diagnosis relies on clinical and lab data.
• Electro interstitial scan (EIS) offers rapid, noninvasive screening for hypertension, sympathetic activity, arterial stiffness, body composition, leptin, and insulin resistance.
• A score of ≥10 CU was initially proposed for metabolic syndrome diagnosis via EIS.

Purpose of the Study:

• To assess the accuracy and validity of EIS for diagnosing metabolic syndrome.
• To determine the optimal cut-off score for metabolic syndrome detection using EIS.

Main Methods:

• A cross-sectional, population-based study involved 253 participants.
• Metabolic syndrome was defined using modified NCEP ATP III and IDF criteria.
• The study determined the most appropriate cut-off score for the EIS instrument.

Main Results:

• Metabolic syndrome prevalence was 48.62% (NCEP ATP III) and 41.11% (IDF).
• A score of ≥10 CU showed low sensitivity (23.6%-27.9%) but high specificity (100%).
• A revised cut-off score of ≥9 CU demonstrated significantly improved diagnostic accuracy, with sensitivity ranging from 79.67% to 88.46% and specificity from 93.29% to 96.92% across both criteria.

Conclusions:

• The initial ≥10 CU cut-off for EIS screening of metabolic syndrome in a Thai population lacks sufficient accuracy.
• A revised cut-off score of ≥9 CU is recommended for enhanced accuracy in metabolic syndrome screening.
• EIS is a safe, rapid, and user-friendly tool for metabolic syndrome screening.