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Updated: Dec 8, 2025

Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
Delayed Presentation of Drug-Induced Hepatic Injury
Shohana Ahmed1, Nirmal K Onteddu2, Ali Jabur1
1Internal Medicine, Texas Tech University Health Sciences Center at Permian Basin, Odessa, USA.
Abstract:
Drug-induced hepatotoxicity is a major cause of acute liver failure (ALF) in the United States. There are many offending agents like prescription drugs and herbal remedies. However, the most common prescription medication involved worldwide is amoxicillin-clavulanate. We report an unusually delayed presentation of severe cholestatic hepatitis caused by amoxicillin-clavulanate in a 20-year-old female with worsening hyperbilirubinemia that was successfully treated with corticosteroids and ursodeoxycholic acid (UDCA).
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