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Articles linked to this work by shared authors, journal, and citation graph.

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Correction: Pérez-Prieto et al. Are Hamstring Grafts a Predisposing Factor to Infection in R-ACL Surgery? A Comparative In Vitro Study. <i>Pathogens</i> 2023, <i>12</i>, 761.

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The vancomycin soaking technique: no differences in autograft re-rupture rate. A comparative study.

Daniel Pérez-Prieto1,2, Simone Perelli3, Ferran Corcoll4

  • 1Department of Traumatology and Orthopaedic Surgery, Hospital del Mar-Universitat Autònoma de Barcelona (UAB), Passeig Marítim, 25, 08003, Barcelona, Spain. dperezprieto@parcdesalutmar.cat.

International Orthopaedics
|September 18, 2020
PubMed
Summary

The vancomycin soaking technique for anterior cruciate ligament reconstruction (ACL-R) is safe, showing no increased re-rupture risk or negative impact on functional outcomes. This study confirms its efficacy in clinical practice.

Keywords:
ACL infectionACL reconstructionInfection preventionOrthopaedic infectionVancomycin technique

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Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Sports Medicine

Background:

  • Anterior cruciate ligament reconstruction (ACL-R) is a common orthopedic procedure.
  • Graft infection prophylaxis is crucial in ACL-R to minimize complications.
  • The vancomycin soaking technique is an emerging method for graft preparation.

Purpose of the Study:

  • To evaluate the re-rupture risk following ACL-R using the vancomycin soaking technique.
  • To compare re-rupture rates and functional outcomes between vancomycin-soaked and non-soaked ACL grafts.
  • To test the hypothesis that vancomycin soaking does not affect re-rupture risk or functional outcomes.

Main Methods:

  • Retrospective historical cohort study comparing two groups of ACL-R patients.
  • Group 1: received pre-operative IV antibiotics. Group 2: received pre-operative IV antibiotics plus vancomycin-soaked graft.
  • Comparison of re-rupture rates and functional outcomes (IKDC, Tegner, Lysholm) at a minimum 5-year follow-up.

Main Results:

  • Re-rupture rates were similar: 4.7% in group 1 vs. 3.9% in group 2 (not significant).
  • Functional outcomes showed no significant difference: IKDC (82.0 vs. 83.9, p=0.049), Tegner (4 vs. 4), Lysholm (90.3 vs. 92.0, p=0.015).
  • The vancomycin soaking technique demonstrated comparable safety and efficacy to standard antibiotic protocols.

Conclusions:

  • The vancomycin soaking technique for ACL autografts is a safe procedure in clinical practice.
  • This technique does not increase the risk of re-rupture after ACL reconstruction.
  • Vancomycin soaking does not negatively impact functional outcomes following ACL-R.