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Published on: September 20, 2024
Post-COVID-19 inflammatory syndrome manifesting as refractory status epilepticus
Elizabeth Carroll1, Henry Neumann2, Maria E Aguero-Rosenfeld3
1Department of Neurology, NYU Langone Medical Center, New York, New York.
Abstract:
There have been multiple descriptions of seizures during the acute infectious period in patients with COVID-19. However, there have been no reports of status epilepticus after recovery from COVID-19 infection. Herein, we discuss a patient with refractory status epilepticus 6 weeks after initial infection with COVID-19. Extensive workup demonstrated elevated inflammatory markers, recurrence of a positive nasopharyngeal SARS-CoV-2 polymerase chain reaction, and hippocampal atrophy. Postinfectious inflammation may have triggered refractory status epilepticus in a manner similar to the multisystemic inflammatory syndrome observed in children after COVID-19.
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