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Updated: Dec 8, 2025

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Imaging guided percutaneous renal biopsy: do it or not?
Francesco Pagnini1, Eleonora Cervi1, Umberto Maestroni2
1Department of Medicine and Surgery, Unit of Radiology, University of Parma, Parma, Italy. massimo.defilippo@unipr.it.
Renal biopsy is crucial for diagnosis and treatment management. The percutaneous approach, often guided by CT or US, is preferred for its sample quality, despite potential complications like hematuria and hematoma.
Area of Science:
- Nephrology
- Interventional Radiology
Background:
- Renal biopsy is integral to diagnosing kidney diseases and guiding therapy.
- Various biopsy techniques exist, including open, laparoscopic, transjugular, transurethral, and percutaneous methods.
Purpose of the Study:
- To review the diagnostic utility and procedural considerations of renal biopsy.
- To compare different renal biopsy techniques and guidance modalities.
Main Methods:
- The percutaneous approach is the current standard of care.
- Guidance options include computed tomography (CT) and ultrasound (US).
- Core needle biopsy is favored over fine-needle aspiration for superior sample quality, particularly for heterogeneous tumors.
Main Results:
- Percutaneous renal biopsy offers advantages in sample acquisition, especially for complex renal masses.
- Common complications include hematuria (1-10%), perinephric hematoma (10-90%), pneumothorax (0.6%), and significant pain (1.2%).
Conclusions:
- Percutaneous renal biopsy, particularly with core needle technique, is a valuable diagnostic tool.
- Understanding the benefits and risks associated with different techniques and guidance methods is essential for patient management.
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