Spontaneous membrane-less multi-compartmentalization via aqueous two-phase separation in complex coacervate micro-droplets
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Updated: Dec 8, 2025

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On-Chip Octanol-Assisted Liposome Assembly for Bioengineering
Published on: March 17, 2023
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Nicolette G Moreau1, Nicolas Martin2, Pierangelo Gobbo1
1Centre for Protolife Research and Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, UK. s.mann@bristol.ac.uk.
Abstract:
Polyelectrolyte/nucleotide multiphase complex coacervate droplets are produced by internalized aqueous two-phase separation and used for the spatially dependent chemical transfer of sugar molecules, providing a step towards the development of membrane-free "organelles" within coacervate-based protocells.
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