Cardiac magnetic resonance in hypertrophic and dilated cardiomyopathies
Silvia Pradella1, Giulia Grazzini2, Cristian De Amicis2
1Department of Radiology, Careggi University Hospital, Largo Brambilla 3, 50134, Florence, Italy. pradella3@gmail.com.
Insights
Cardiac magnetic resonance (CMR) is crucial for diagnosing cardiomyopathies. This imaging technique precisely evaluates hypertrophic and dilated forms, identifying fibrosis and tissue changes for accurate diagnosis.
Area of Science:
- Cardiology
- Medical Imaging
- Genetics
Background:
- Cardiomyopathies are diverse heart muscle diseases with evolving classifications.
- Genetic advancements increasingly identify disease origins.
- Imaging modalities are essential for defining cardiomyopathy phenotypes.
Purpose of the Study:
- To review Cardiac Magnetic Resonance (CMR) features in hypertrophic and dilated cardiomyopathies.
- To discuss differential diagnoses using CMR.
- To highlight CMR's role in myocardial tissue characterization.
Main Methods:
- Review of current literature on CMR in cardiomyopathies.
- Focus on morphological and tissue characterization sequences.
- Analysis of CMR findings in hypertrophic and dilated cardiomyopathy.
Main Results:
- CMR precisely measures wall thickness, ventricular size, and function in hypertrophic cardiomyopathy.
- CMR detects fibrosis and quantifies myocardial tissue changes (T1 mapping, extracellular volume).
- CMR is the gold standard for assessing ventricular volumes in dilated cardiomyopathy and reveals myocardial alterations.
Conclusions:
- CMR is invaluable for characterizing hypertrophic and dilated cardiomyopathies.
- CMR's tissue characterization capabilities aid in differential diagnosis.
- CMR provides comprehensive morphological and functional assessment of cardiomyopathies.
Abstract:
Cardiomyopathies are a heterogeneous entity. The progress in the field of genetics has allowed over the years to determine its origin more and more often. The classification of these pathologies has changed over the years; it has been updated with new knowledge. Imaging allows to define the phenotypic characteristics of the different forms of cardiomyopathy. Cardiac magnetic resonance (CMR) allows a morphological evaluation of the associated (and sometimes pathognomonic) cardiac findings of any form of cardiomyopathy. The tissue characterization sequences also make magnetic resonance imaging unique in its ability to detect changes in myocardial tissue. This review aims to define the features that can be highlighted by CMR in hypertrophic and dilated forms and the possible differential diagnoses. In hypertrophic forms, CMR provides: precise evaluation of wall thickness in all segments, ventricular function and size and evaluation of possible presence of areas of fibrosis as well as changes in myocardial tissue (measurement of T1 mapping and extracellular volume values). In dilated forms, cardiac resonance is the gold standard in the assessment of ventricular volumes. CMR highlights also the potential alterations of the myocardial tissue.
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