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Racial Disparities in COVID-19 Hospitalization and In-hospital Mortality at the Height of the New York City Pandemic
Benjamin D Renelus1, Neil C Khoury2, Karthik Chandrasekaran2
1Division of Gastroenterology and Hepatology, Morehouse School of Medicine, Atlanta, GA, USA.
Insights
Blacks faced higher COVID-19 hospitalization rates compared to Whites. Hispanics experienced greater in-hospital mortality. Further research is needed to understand these racial disparities in coronavirus disease-2019 outcomes.
Area of Science:
- Public Health
- Epidemiology
- Health Disparities
Background:
- The coronavirus disease-2019 (COVID-19) pandemic disproportionately affected minority populations.
- Understanding racial disparities in COVID-19 outcomes is crucial for targeted public health interventions.
Purpose of the Study:
- To investigate the association between race and hospitalization rates for COVID-19.
- To examine the relationship between race and in-hospital survival among COVID-19 patients during the pandemic's peak in New York City.
Main Methods:
- A retrospective cohort study of 734 hospitalized COVID-19 patients in New York City.
- Comparison of hospitalization rates with regional population data by race.
- Analysis of in-hospital survival using Cox proportional hazards regression.
Main Results:
- Black patients were nearly twice as likely to be hospitalized for COVID-19 compared to White patients (OR 1.89).
- Hispanic patients showed a significantly higher hazard of in-hospital mortality compared to White patients (HR 1.84).
- A non-significant trend of increased in-hospital mortality was observed for Black patients compared to White patients (HR 1.30).
Conclusions:
- Racial disparities exist in COVID-19 hospitalization and mortality.
- Black individuals faced higher hospitalization risks, while Hispanic individuals experienced greater in-hospital mortality.
- Socioeconomic factors contributing to these disparities require further national-level investigation.
Objectives:
Investigate whether or not race is associated with differences in hospitalization and survival to discharge among patients with coronavirus disease-2019 (COVID-19) at the height of the pandemic in New York City (NYC).
Methods:
Single-center retrospective cohort study of COVID-19 patients hospitalized at our university-affiliated NYC hospital from 3/10/20 through 4/13/20 with follow-up to 5/1/20. Our primary endpoint was hospitalization rate among patients with confirmed COVID-19 compared with the regional population based on race. Our secondary endpoint survival to discharge among hospitalized COVID-19 patients. NYC Department of Health data were used to calculate hospitalization odds ratios. Chi-square and t tests were used to compare categorial and continuous variables, respectively. Cox proportional hazards regression and predictive analysis were used to investigate our endpoints further.
Results:
Our cohort of 734 patients included 355 women (48.4%), 372 Blacks (50.7%), 214 Whites (29.2%), and 92 Hispanics (12.5%) in our analysis. Blacks were nearly twice as likely as Whites to require hospitalization for COVID-19 (OR 1.89, 95% CI, 1.59-2.24, p < 0.001). Hispanics were also more likely to suffer in-hospital mortality from COVID-19 compared with Whites (HR 1.84; 95% CI 1.21-2.80; p = 0.005). There was a non-significant increased hazard of in-hospital mortality among Blacks when compared with Whites (HR, 1.30; 95% CI, 0.95-1.78; p = 0.09).
Conclusions And Relevance:
Blacks were more likely than Whites to require hospitalization for COVID-19 while Hispanics were more likely to experience in-hospital mortality. Further investigation into the socioeconomic factors underlying racial disparities in COVID-19 survival and severity requiring hospitalization is needed on a national scale.
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