Antioxidant activities and mechanisms of polysaccharides
Si Mu1, Wenjian Yang1, Gangliang Huang1
1Active Carbohydrate Research Institute, Chongqing Key Laboratory of Green Synthesis and Application, College of Chemistry, Chongqing Normal University, Chongqing, China.
Abstract:
Polysaccharide, as one of the effective components of traditional Chinese medicine, has the activities of anti-oxidation, anti-virus, improving immunity and so on. Chinese herbal polysaccharides have a wide range of sources. It is found that polysaccharides in many plants and microorganisms have significant antioxidant effects, mainly through the endogenous antioxidant stress Nrf2/ARE pathway to regulate the expression of downstream antioxidant enzymes. These antioxidant enzymes can further block the free radical chain reaction, thus reducing the generation of free radicals. Secondly, by inhibiting the expression of iNOS mRNA and reducing NO production, it can significantly increase the antioxidant capacity and reduce oxidative stress injury. Polysaccharides are rich in natural resources, their multi-channel, multi-target, multi-effect, and other characteristics have made great progress in antioxidants.
Related Concept Videos
Biosynthesis of Polysaccharides
Radical Autoxidation
Chemistry of Carbohydrates
Cellulose and Pectic Polysaccharides
As a cell matures, its cell wall specializes according to its type. For example, the...
Introduction to Carbohydrates
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:


