Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Osmosis and Osmotic Pressure of Solutions02:40

Osmosis and Osmotic Pressure of Solutions

45.1K
A number of natural and synthetic materials exhibit selective permeation, meaning that only molecules or ions of a certain size, shape, polarity, charge, and so forth, are capable of passing through (permeating) the material. Biological cell membranes provide elegant examples of selective permeation in nature, while dialysis tubing used to remove metabolic wastes from blood is a more simplistic technological example. Regardless of how they may be fabricated, these materials are generally...
45.1K
Osmosis01:30

Osmosis

10.0K
Osmosis is the movement of free water molecules through a semipermeable membrane.  The water's concentration gradient across the membrane is inversely proportional to the solutes' concentration. Whereas diffusion transports material across membranes and within cells, osmosis transports only water across a membrane, and the membrane limits the diffusion of solutes in the water. Osmosis is a special case of diffusion.
Water, like other substances, moves from a high concentration of...
10.0K
Osmosis00:47

Osmosis

191.0K
Approximately 60% to 95% of the weight of living organisms is attributed to water. Therefore, maintaining appropriate water balance within cells is of paramount importance. Osmosis is the movement of water across a semipermeable membrane, such as a cell’s plasma membrane. In living organisms, water plays a crucial role as a solvent—a molecule that dissolves other molecules.
191.0K
Factors Influencing Microbial Growth: Osmolarity01:28

Factors Influencing Microbial Growth: Osmolarity

525
Osmolarity is the measure of solute concentration in a solution. It plays a critical role in determining water availability for organisms. Water moves across semipermeable membranes through osmosis, flowing from regions of lower solute concentration (more dilute) to regions of higher solute concentration (more concentrated).In high-solute environments, microbial cells lose water, leading to dehydration and inhibited growth. The extent to which water is available to microbes in such environments...
525
Phase Transitions: Melting and Freezing02:39

Phase Transitions: Melting and Freezing

14.3K
Heating a crystalline solid increases the average energy of its atoms, molecules, or ions, and the solid gets hotter. At some point, the added energy becomes large enough to partially overcome the forces holding the molecules or ions of the solid in their fixed positions, and the solid begins the process of transitioning to the liquid state or melting. At this point, the temperature of the solid stops rising, despite the continual input of heat, and it remains constant until all of the solid is...
14.3K
Phase Transitions: Vaporization and Condensation02:39

Phase Transitions: Vaporization and Condensation

20.2K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...
20.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

8% capsaicin patches for HIV-induced polyneuropathy: a systematic review and meta-analysis.

Pain management·2026
Same author

Refractory Chronic Neuropathic Pain Successfully Treated With Scrambler Therapy.

The primary care companion for CNS disorders·2026
Same author

Intrathecal baclofen pump failure due to pain-induced autonomic dysreflexia.

BMJ case reports·2026
Same author

Evaluation of the Gigstride wearable device for pain reduction and functional outcomes in patients with lower extremity mobility deficits: a single-arm pilot feasibility study.

Pain management·2026
Same author

Inferior Outcomes of p230-CML with Imatinib: a Report of 2 Cases of p210/p230 Co-Expressed CML Showing Rapid Progression To Leukaemia Cutis along with the Systematic Review.

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion·2026
Same author

Polyamine homeostasis in Caenorhabditis elegans relies primarily on transport.

Cell reports·2026
Same journal

Thyroid cancer-associated EZH1 Q571R mutation drives chromatin compaction and H3K27me3 invasion into active chromatin.

Molecular cell·2026
Same journal

Genome-wide rotational and translational phasing of nucleosomes with human transcription factors.

Molecular cell·2026
Same journal

Spliceosomal proofreading factors safeguard 3' splice-site fidelity and prevent proteotoxicity and inflammation.

Molecular cell·2026
Same journal

Cytosolic EZH2-IMPDH2 complexes regulate melanoma progression and metastasis via GTP.

Molecular cell·2026
Same journal

A bacterial reverse transcriptase: Protein-templated DNA synthesis fuels antiviral immunity.

Molecular cell·2026
Same journal

Tweezing apart ribosome heterogeneity.

Molecular cell·2026
See all related articles

Related Experiment Video

Updated: Dec 8, 2025

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis
08:08

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis

Published on: February 19, 2018

8.8K

Osmotic Stress Triggers Phase Separation.

Sumit Majumder1, Ankur Jain2

  • 1Whitehead Institute for Biomedical Research, Cambridge, MA, USA.

Molecular Cell
|September 18, 2020
PubMed
Summary
This summary is machine-generated.

Osmotic stress rapidly and reversibly condenses multivalent proteins within cells. This volume change mechanism is crucial for cellular adaptation and protein regulation.

More Related Videos

Phosphoproteomic Strategy for Profiling Osmotic Stress Signaling in Arabidopsis
05:47

Phosphoproteomic Strategy for Profiling Osmotic Stress Signaling in Arabidopsis

Published on: June 25, 2020

5.5K
Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.5K

Related Experiment Videos

Last Updated: Dec 8, 2025

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis
08:08

Monitoring the Effect of Osmotic Stress on Secretory Vesicles and Exocytosis

Published on: February 19, 2018

8.8K
Phosphoproteomic Strategy for Profiling Osmotic Stress Signaling in Arabidopsis
05:47

Phosphoproteomic Strategy for Profiling Osmotic Stress Signaling in Arabidopsis

Published on: June 25, 2020

5.5K
Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy
10:08

Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

Published on: October 24, 2017

9.5K

Area of Science:

  • Cell biology
  • Biophysics

Background:

  • Cell volume regulation is critical for cellular homeostasis.
  • Osmotic stress challenges cell volume and integrity.

Purpose of the Study:

  • To investigate the molecular mechanisms underlying cell volume changes during osmotic stress.
  • To determine the role of protein condensation in cellular response to osmotic stress.

Main Methods:

  • Microscopy techniques to observe protein behavior.
  • Osmotic stress induction in cell models.
  • Analysis of protein multivalency and condensation.

Main Results:

  • Cell volume reduction upon osmotic stress triggers rapid protein condensation.
  • Condensation is reversible upon restoration of isotonic conditions.
  • Numerous multivalent proteins participate in this process.

Conclusions:

  • Cell volume changes are a direct trigger for rapid, reversible protein condensation.
  • This mechanism represents a novel cellular response to osmotic stress, impacting protein function and localization.