Related Experiment Video
Updated: Dec 8, 2025
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
Adherence to oral chemotherapy among colorectal cancer patients: A longitudinal study
Yilin Chen1, Xiaodan Wu2, Xuemei Xian1
1Sir Run Run Shaw Hospital, School of medicine, Zhejiang University, Hangzhou, China.
Purpose:
The aims of this study were (1) to describe adherence to oral chemotherapy among colorectal cancer patients on different courses of chemotherapy, and (2) to explore the associated factors with oral chemotherapy adherence in colorectal cancer patients.
Method:
This investigation was a longitudinal study. We selected a convenience sample of 132 patients with colorectal cancer. We finished a six-month follow-up investigation by a questionnaire at different stages of chemotherapy.
Results:
The percentage of colorectal cancer patients who had poor overall oral chemotherapy adherence was 71.4%, and adherence declined over the course of chemotherapy. According to a logistic regression analysis, whether the patients lived with their parents, job status during chemotherapy and their health benefits were related to oral chemotherapy adherence.
Conclusions:
This study showed that overall oral chemotherapy adherence among Chinese colorectal cancer patients was poor, especially during the last stage of chemotherapy, and adherence showed a downward trend during chemotherapy. The adherence could be improved by interventions related to family, work and patients' perception of oral chemotherapy.
More Related Videos
Related Concept Videos
01:27Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
02:56Treatment Resistant Cancers
01:21Cancer Survival Analysis
02:20Longitudinal Research
02:49Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
01:25Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...