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High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Human Health Risk Assessment through Roasted Meats Consumption
Luana C S Leite1, Elaine S de P Melo1, Daniela G Arakaki1
1Group of Spectroscopy and Bioinformatics Applied to Biodiversity and Health, School of Medicine, Postgraduation Program in Health and Development in the Midwest Region, Faculty of Medicine, Federal University of Mato Grosso do Sul, Campo Grande MS 79079-900, Brazil.
Roasted meats contain varying metal and metalloid levels depending on the fuel source. While generally safe, arsenic in some wood-roasted meats exceeds limits, posing potential long-term health risks.
Area of Science:
- Food Science and Technology
- Environmental Health
- Analytical Chemistry
Background:
- Limited data exists on metal and metalloid content in meats roasted with different woods and charcoals.
- Roasting methods can influence the elemental composition of meat, impacting nutritional and safety profiles.
- Understanding these variations is crucial for assessing potential health risks associated with roasted meat consumption.
Purpose of the Study:
- To quantify metals (Al, Cr, Cd, Cu, Fe, Mg, Mn, Mo, Ni, V, Zn) and metalloid (As) in roasted meats.
- To compare elemental concentrations based on roasting fuel (wood vs. charcoal).
- To assess the Estimated Daily Intake (EDI) and Hazard Quotient (HQ) for adults to evaluate health risks.
Main Methods:
- Inductively Coupled Plasma Mass Spectrometry (ICP-OES) was used for elemental analysis.
- Microwave digestion was employed for sample preparation.
- Estimated Daily Intake (EDI) and Hazard Quotient (HQ) calculations were performed for risk assessment.
Main Results:
- Raw meats showed lower Al, Cr, Cu, and Fe than reported internationally, but higher As, Mg, V, and Zn.
- Meats roasted with wood exhibited elevated levels of Mg, As, Cr, Fe, V, and Zn compared to raw meat.
- Arsenic content was significantly higher in meat roasted with CCA-treated wood compared to charcoal-roasted meat.
Conclusions:
- Wood-roasting results in higher concentrations of major and trace elements in meat than coal-roasting.
- While overall exposure is minimal, elevated arsenic levels in some wood-roasted meats warrant attention.
- Long-term high exposure to certain elements from roasted meats may pose health concerns.
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