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Egg white hydrolyzate reduces mental fatigue: randomized, double-blind, controlled study
Mariko Oe1, Hisae Sakamoto1, Hiroshi Nishiyama1
1R&D Division, Kewpie Corporation, 2-5-7, Sengawa-cho, Chofu-shi, Tokyo, Japan.
BMC Research Notes
|September 19, 2020
Summary
Ingesting egg white hydrolyzate (EWH) boosts antioxidant capacity after a single dose and reduces mental fatigue following two weeks of consumption in athletes.
Area of Science:
- Sports Science
- Nutritional Biochemistry
- Human Physiology
Background:
- Athletes experience significant physical and mental fatigue.
- Oxidative stress is a concern for athletic performance.
- Egg white hydrolyzate (EWH) is a protein-derived supplement with potential ergogenic benefits.
Purpose of the Study:
- To evaluate the effect of egg white hydrolyzate (EWH) on antioxidant capacity.
- To determine the efficacy of EWH in reducing mental fatigue in athletes.
- To investigate the dose-response and duration of EWH supplementation.
Main Methods:
- Two randomized controlled trials were conducted.
- Study 1: Single dose of 5g EWH or placebo in 19 athletes.
- Study 2: 2-week intake of 5g EWH or placebo daily in 74 athletes.
Main Results:
- A single dose of EWH significantly enhanced antioxidant capacity compared to placebo (p < 0.05).
- Two weeks of EWH supplementation significantly reduced mental fatigue (p < 0.05).
- No significant differences were observed in oxidative stress markers in Study 1.
Conclusions:
- Egg white hydrolyzate (EWH) demonstrates acute benefits for antioxidant capacity.
- Sustained intake of EWH effectively mitigates mental fatigue in athletic populations.
- EWH shows promise as a nutritional supplement for athletes to manage fatigue and oxidative stress.

