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Updated: Dec 8, 2025

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
Published on: June 6, 2025
Risk factors for infection complications after transrectal ultrasound-guided transperineal prostate biopsy
Xue-Fei Ding1, Yang Luan2, Sheng-Ming Lu1
1Clinical Medical College, Yangzhou University, No. 98 West Nantong Road, Yangzhou, 225001, Jiangsu Province, China.
Background:
To investigate the influence factors of infection complications of transrectal ultrasound-guided transperineal prostate biopsy.
Methods:
A total of 2192 patients who underwent prostate biopsy under transperineal prostate biopsy were analyzed retrospectively from December 2010 to May 2020.We collected the clinical characteristics and the incidence of complications, and used univariate and multivariate logistic regression analyses to analyze independent risk factors for infection complications after transperineal prostate biopsy.
Results:
Univariate analysis showed that the following factors were associated with the infection complications: diabetes, bacterial prostatitis, history of urinary retention, history of urinary infection, and number of cores. Furthermore, multivariate logistic analysis revealed that diabetes (OR 2.037, 95% CI 1.143-3.572, P = 0.021) and history of urinary retention (OR 2.563, 95% CI 1.284-3.901, P = 0.013) were independent risk factors for infection complications after transperineal prostate biopsy.
Conclusions:
Patients with diabetes and history of urinary retention were more likely to have infection complications after transperineal prostate biopsy.
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