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Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline
Connie B Newman1, Michael J Blaha2, Jeffrey B Boord3
1Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, New York University Grossman School of Medicine, New York, New York.
The Journal of Clinical Endocrinology and Metabolism
|September 20, 2020
Summary
This guideline offers endocrinologists strategies for managing dyslipidemia in patients with endocrine diseases to prevent cardiovascular events. It reviews evidence on treating endocrine disorders to improve lipid levels and reduce cardiovascular disease risk.
Area of Science:
- Endocrinology
- Cardiovascular Medicine
- Metabolic Disorders
Background:
- Dyslipidemia is common in endocrine diseases.
- Endocrine disorders can increase the risk of atherosclerotic cardiovascular disease (ASCVD).
- Triglyceride-induced pancreatitis is a concern in some dyslipidemias.
Purpose of the Study:
- To provide an approach for assessing and treating dyslipidemia in patients with endocrine diseases.
- To prevent cardiovascular events and triglyceride-induced pancreatitis.
- To review evidence on the impact of treating endocrine diseases on dyslipidemia and ASCVD risk.
Main Methods:
- Guideline development based on available evidence.
- Review of data on dyslipidemia and ASCVD risk in endocrine disorders.
- Analysis of evidence for correcting dyslipidemia by treating the underlying endocrine disease.
Main Results:
- Treatment of endocrine disease may improve lipid abnormalities.
- Evidence is discussed regarding the reduction of ASCVD risk by treating endocrine disorders.
- Recommendations are formulated for assessment and management.
Conclusions:
- Endocrine disease management can improve lipid profiles.
- The impact of endocrine disease treatment on cardiovascular outcomes is evaluated.
- Guidelines are established for managing dyslipidemia in this patient population.
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