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Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
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Predicting Equations and Resting Energy Expenditure Changes in Overweight Adults
Mojca Stubelj1, Kaja Teraž2, Tamara Poklar Vatovec1
1University of Primorska, Faculty of Health Sciences, Polje 42, 6310 Izola, Slovenia.
Zdravstveno Varstvo
|September 21, 2020
Summary
Accurate estimation of resting energy expenditure (REE) is crucial for weight management. This study found Owen's equation to be most comparable to measured REE, which decreased after a 6-month weight loss program.
Area of Science:
- Nutrition Science
- Metabolic Research
- Obesity Studies
Background:
- Resting energy expenditure (REE) is a key metabolic parameter.
- Accurate REE assessment is vital for effective weight management and diet therapy.
- Weight loss interventions can alter REE, necessitating precise measurement or estimation.
Purpose of the Study:
- To compare measured REE with values estimated by various equations and a body composition analyzer.
- To assess changes in REE after a 6-month weight loss intervention program.
- To identify the most accurate estimation method for REE in adults undergoing weight loss.
Main Methods:
- 33 healthy adults (25-49 years) with overweight/obesity (BMI 29.1-29.8 kg/m²) participated.
- Measured REE using indirect calorimetry (MedGem® Microlife).
- Estimated REE using Harris-Benedict, Mifflin-St Jeor, Owen, Wright equations, and Tanita analyzer, pre- and post-intervention.
Main Results:
- Significant differences found between measured REE and estimates from Harris-Benedict, Mifflin-St Jeor, Wright equations, and Tanita analyzer for females.
- Significant differences noted between measured REE and estimates from Harris-Benedict and Wright equations for males.
- Significant discrepancies observed between measured REE and Tanita-derived estimates for both sexes.
Conclusions:
- Owen's equation demonstrated the highest comparability to measured REE in this cohort.
- A significant decrease in measured REE was observed post-weight loss.
- Adjusting diet therapy based on post-intervention REE is recommended.
Keywords:
energy expenditureindirect calorimetryobesitypredictive equationsresting energy expenditureMore Related Videos
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