Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

DXplain. An evolving diagnostic decision-support system.

G O Barnett, J J Cimino, J A Hupp

    JAMA
    |July 3, 1987
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Harvard-MIT-NEMC Research Training Program in Medical Informatics.

    Yearbook of medical informatics·2016
    Same author

    Coding Systems in Health Care.

    Yearbook of medical informatics·2016
    Same author

    Medical Informatics Training at Columbia University and the Columbia-Presbyterian Medical Center.

    Yearbook of medical informatics·2016
    Same author

    Point-of-Care Knowledge-Based Resource Needs of Clinicians: A Survey from a Large Academic Medical Center.

    Applied clinical informatics·2015
    Same author

    A complementary graphical method for reducing and analyzing large data sets. Case studies demonstrating thresholds setting and selection.

    Methods of information in medicine·2014
    Same author

    The false security of blind dates: chrononymization's lack of impact on data privacy of laboratory data.

    Applied clinical informatics·2013
    Same journal

    Alcohol-Related Liver Disease: A Review.

    JAMA·2026
    Same journal

    Online Prescribing of GLP-1 Receptor Agonists.

    JAMA·2026
    Same journal

    Using AI Disagreement to Expose Gaps in Coverage Rules.

    JAMA·2026
    Same journal

    Randomized Trials in Pregnancy.

    JAMA·2026
    Same journal

    Randomized Trials in Pregnancy-Reply.

    JAMA·2026
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    See all related articles

    DXplain is a computer-based diagnostic decision-support system that assists physicians by generating diagnostic hypotheses from clinical manifestations. It provides explanations and access to a medical knowledge base, with user feedback driving its enhancement.

    Area of Science:

    • Medical Informatics
    • Clinical Decision Support Systems

    Background:

    • Physicians require efficient tools for differential diagnosis.
    • Computer-based systems can aid in interpreting complex clinical data.

    Purpose of the Study:

    • To introduce DXplain, a user-friendly diagnostic decision-support system for physicians.
    • To describe DXplain's functionality in generating and justifying diagnostic hypotheses.

    Main Methods:

    • DXplain accepts lists of clinical manifestations as input.
    • It generates diagnostic hypotheses with explanations and justifications.
    • The system provides access to a differential diagnosis knowledge base.

    Main Results:

    • DXplain offers a structured approach to diagnostic reasoning.

    Related Experiment Videos

  • The system facilitates physician access to relevant medical knowledge.
  • User collaboration is integral to system improvement.

    • Conclusions:

    • DXplain serves as a valuable tool for physicians, regardless of computer expertise.
    • Continuous user feedback is crucial for refining the diagnostic knowledge base and system functionality.