Related Experiment Video
Updated: Dec 8, 2025

A Microplate Assay to Assess Chemical Effects on RBL-2H3 Mast Cell Degranulation: Effects of Triclosan without Use of an Organic Solvent
Published on: November 1, 2013
Triclosan: antimicrobial mechanisms, antibiotics interactions, clinical applications, and human health
Prabin Shrestha1, Yongmei Zhang2, Wen-Jen Chen1
1Biological Sciences Department, University of Memphis, Memphis, Tennessee, USA.
Abstract:
The large-scale applications of Triclosan in industrial and household products have created many health and environmental concerns. Despite the fears of its drug-resistance and other issues, Triclosan is still an effective drug against many infectious organisms. Knowing the cross-interactions of Triclosan with different antibiotics, bacteria, and humans can provide much-needed information for the risk assessment of this drug. We review the current understanding of the antimicrobial mechanisms of Triclosan, how microbes become resistant to Triclosan, and the synergistic and antagonistic effects of Triclosan with different antibiotics. Current literature on the clinical applications of Triclosan and its effect on fetus/child development are also summarized.
More Related Videos
08:22Author Spotlight: A New and Efficient Method for Comprehensive Metabolite Cytotoxicity Assessment of Triazole Pesticides in Plants
Published on: December 22, 2023
07:47Anti-virulent Disruption of Pathogenic Biofilms using Engineered Quorum-quenching Lactonases
Published on: January 1, 2016
Related Concept Videos
Antimicrobial Effectiveness
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Pharmacokinetics: Drug–Drug Interactions
Gene Regulation in Microbial Communities: Quorum Sensing
Hand hygiene
Hand washing...
Chemical Agents for Microbial Control