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Does COVID-19 Involve the Retina?

Michael Karampelas1, Maria Dalamaga2, Irene Karampela3

  • 1Medical Retina Department, Hippokration General Hospital, Athens, Greece. mikekarampelas@hotmail.com.

Ophthalmology and Therapy
|September 21, 2020
PubMed
Summary
This summary is machine-generated.

COVID-19 can affect endothelial cells throughout the body, including the retina, potentially causing microvascular issues. Ocular symptoms like new scotoma warrant retinal examination and follow-up post-infection.

Keywords:
COVID-19MicroangiopathyRetinaSARS-CoV-2

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Area of Science:

  • Ophthalmology
  • Virology
  • Pathology

Background:

  • COVID-19 impacts endothelial cells in multiple organs, with evidence of endotheliitis and vasculitis.
  • Viral RNA detection in the retina and reports of retinal microangiopathy suggest ocular involvement in COVID-19.

Purpose of the Study:

  • To emphasize the importance of reporting ocular symptoms in COVID-19 patients.
  • To highlight the potential need for retinal examinations and follow-up testing.

Main Methods:

  • Review of histopathological evidence and recent publications on COVID-19 and ocular manifestations.

Main Results:

  • Endothelial cell dysfunction is a hallmark of COVID-19 affecting various organs.
  • Retinal involvement, including viral RNA detection and microangiopathy, is increasingly recognized.

Conclusions:

  • Clinically significant ocular symptoms in COVID-19 patients require thorough reporting.
  • New scotoma may indicate the need for prompt retinal evaluation and post-recovery monitoring.