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Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
A case of pancreatic arteriovenous malformation caused acute pancreatitis
Kohei Nagata1, Kazuto Tajiri1, Nozomu Muraishi1
1Third Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
Abstract:
Arteriovenous malformation (AVM) in the pancreas rarely causes acute pancreatitis. However, even when it does cause pancreatitis, the pathogenesis is unclear. A 61-year-old man was admitted to our hospital for acute pancreatitis. The findings of computed abdominal tomography, magnetic resonance imaging, and endoscopic ultrasonography revealed pancreatic AVM and hematoma in the tail of the pancreas. These lesions were suspected to be associated with pancreatitis. Although endoscopic retrograde pancreatography could not confirm hemosuccus pancreaticus, distal pancreatectomy was performed because of repeated pancreatitis. The histopathological findings of the resected specimen revealed rupture of the AVM vessels into the main pancreatic ducts. Finally, we considered that intermittent bleeding due to AVM rupture and hematoma formation in the main pancreatic duct caused the repeated pancreatitis.
Insights
Pancreatic arteriovenous malformation (AVM) can cause acute pancreatitis through vessel rupture into ducts. This study clarifies the pathogenesis of pancreatitis linked to pancreatic AVM and hematoma formation.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Surgical Pathology
Background:
- Pancreatic arteriovenous malformations (AVMs) are rare causes of acute pancreatitis.
- The exact pathogenesis of pancreatitis associated with pancreatic AVMs remains unclear.
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