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Handheld Optical Coherence Tomography in a Young Infant With Albinism and Fovea Plana
Sohaib R Rufai1, Helena Lee, Irene Gottlob
1The University of Leicester Ulverscroft Eye Unit (SRR, IG), Leicester Royal Infirmary, Leicester, United Kingdom; Department of Ophthalmology (SRR), Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom; and Clinical and Experimental Sciences (HL), Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Abstract:
We present handheld optical coherence tomography (OCT) diagnosis of Grade 4 foveal hypoplasia (fovea plana) in a 28-day-old infant with albinism. Grade 4 foveal hypoplasia is characterized by the absence of the foveal pit, absence of outer segment lengthening, and absence of outer nuclear layer widening. Binocular visual acuity at 58 months follow-up was 1.2 logarithm of the minimal angle of resolution (logMAR). We describe our handheld OCT acquisition protocol and compare the morphological features with a healthy, age-matched control subject.
