Related Experiment Video
Updated: Dec 8, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
The Effect of Psychosocial Work Factors on Headache: Results From the PRISME Cohort Study
Caroline Urhammer1, Matias Brødsgaard Grynderup, Andreas Moses Appel
1Department of Public Health, University of Copenhagen, Copenhagen, Denmark (Urhammer, Appel, Dr AM Hansen, Dr Nabe-Nielsen); Department of Psychology, University of Copenhagen, Copenhagen, Denmark (Dr Grynderup); The National Research Centre for the Working Environment, Copenhagen, Denmark (Dr AM Hansen); Danish Headache Center, Rigshospitalet-Glostrup, Glostrup, Denmark (Dr JM Hansen), Danish Headache Knowledge Center, Rigshospitalet-Glostrup, Glostrup, Denmark (Dr JM Hansen); Research Unit of Clinical Epidemiology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark (Dr Kaerlev); Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark (Dr Kaerlev).
Objective:
To investigate the cross-sectional and longitudinal association between psychosocial work factors, assessed as work-unit averages, and headache. For comparison, we also applied individual exposure measures.
Methods:
We used questionnaire-data on headache and psychosocial work factors (PWF). In total, 2247 employees were included in the cross-sectional analyses and 553 in the longitudinal analyses using work-unit averages. The corresponding numbers for the analyses using individual exposure measures were 4261 and 942 employees.
Results:
Low skill discretion and low decision authority were most consistently associated with higher odds of headache across all analyses. Role conflicts, bullying, and effort-reward imbalance were associated with headache in some analyses. All PWF were associated with headache in cross-sectional analyses with individual exposure measures.
Conclusion:
This study partly supports the hypothesis of an effect of PWF, as a source of psychological stress, on the risk of headache.
Related Concept Videos
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...

