Synthesis of enriched boron nitride nanocrystals: A potential element for biomedical applications

The shortcomings in Boron neutron capture therapy (BNCT) and Hyperthermia for killing the tumor cell desired for the synthesis of a new kind of material suitable to be first used in BNCT and later on enable the conditions for Hyperthermia to destroy the tumor cell. The desire led to the synthesis of large band gap semiconductor nano-size Boron-10 enriched crystals of hexagonal boron nitride (¹⁰BNNCs). The contents of ¹⁰BNNCs are analyzed with the help of x-ray photoelectron spectroscopy (XPS) and counter checked with Raman and XRD. The ¹⁰B-contents in ¹⁰BNNCs produce ⁷Li and ⁴He nuclei. A Part of the ⁷Li and ⁴He particles released in the cell is allowed to kill the tumor (via BNCT) whereas the rest produce electron-hole pairs in the semiconductor layer of ¹⁰BNNCs suggested to work in Hyperthermia with an externally applied field.