Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

452
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
452
Stress and Mental Health01:30

Stress and Mental Health

387
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
387
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

970
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
970
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

562
Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
562
Bullying02:04

Bullying

8.7K
A modern form of aggression is bullying. As you learn in your study of child development, socializing and playing with other children is beneficial for children’s psychological development. However, as you may have experienced as a child, not all play behavior has positive outcomes. Some children are aggressive and want to play roughly. Other children are selfish and do not want to share toys. One form of negative social interactions among children that has become a national concern is...
8.7K
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

307
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
307

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Effects of Adverse Childhood Experiences on Adult Mental Health Across Gender, Race/Ethnicity, and Economic Status in the United States: A Systematic Review and Meta-Analysis.

Trauma, violence & abuse·2026
Same author

Dimensional Modeling of Adverse Childhood Experiences: An Empirical Analysis and Critique.

Child maltreatment·2026
Same author

Addressing the Neglect of Emotional Neglect: Prevalence and Long-Term Consequences in a Low-Income Sample.

Child maltreatment·2026
Same author

Symptom burden, healthcare utilization, and risky behaviors in survivors of the childhood cancer survivor study (CCSS): an observation cohort study.

EClinicalMedicine·2025
Same author

Reexamining the Evidence-Based Practice Attitude Scale-36 (EBPAS-36) in a U.S. sample of trauma-focused treatment providers.

Implementation science communications·2025
Same author

Addressing Maternal and Child Health Disparities Through Perinatal Home Visiting.

WMJ : official publication of the State Medical Society of Wisconsin·2025

Related Experiment Video

Updated: Dec 8, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

632

Childhood polyvictimization and marijuana use trajectories.

ChienTi Plummer Lee1, Joshua Mersky1, Ian Marsee2

  • 1Helen Bader School of Social Welfare, University of Wisconsin at Milwaukee, Milwaukee, WI, USA.

Development and Psychopathology
|September 22, 2020
PubMed
Summary

Childhood polyvictimization significantly increases the risk of adolescent marijuana use, leading to earlier onset, higher frequency, and dependence symptoms. Targeted interventions are crucial for at-risk youth.

Keywords:
Add Healthmarijuanapolyvictimizationtrauma

More Related Videos

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.2K
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

509

Related Experiment Videos

Last Updated: Dec 8, 2025

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
07:51

Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice

Published on: August 1, 2025

632
Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
07:30

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

7.2K
Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
05:13

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

509

Area of Science:

  • Adolescent Health
  • Developmental Psychology
  • Substance Use Research

Background:

  • Recreational marijuana use poses risks to adolescent health and development.
  • Understanding marijuana use trajectories and predictors is vital for intervention.
  • Childhood polyvictimization is a potential risk factor for adolescent substance use.

Purpose of the Study:

  • To examine the impact of childhood polyvictimization on marijuana use onset, trajectory, and dependence symptoms in adolescents.
  • To identify distinct marijuana use subgroups among adolescents.
  • To investigate the association between polyvictimization and these marijuana use patterns.

Main Methods:

  • Utilized data from 15,960 participants in the National Longitudinal Study of Adolescent to Adult Health.
  • Employed variable-centered approaches and Zero-Inflated Poisson latent class growth analysis (ZIP-LCGA).
  • Tested associations using multinomial logit regression within ZIP-LCGA.

Main Results:

  • Marijuana use increased through adolescence, peaked in early adulthood, and declined thereafter.
  • Childhood polyvictimization was linked to earlier marijuana onset, increased use frequency, and more dependence symptoms.
  • Four marijuana use subgroups were identified: non-users, adolescence-limited, escalators, and chronic users. Polyvictimization differentiated non-users from all user groups.

Conclusions:

  • Childhood polyvictimization has lasting developmental implications, significantly influencing adolescent marijuana use patterns.
  • Children experiencing polyvictimization are a key group for targeted interventions to prevent problematic marijuana use.
  • Findings highlight the need for early intervention strategies addressing childhood trauma to mitigate risks of substance use disorders.