Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular characterization and correlation with β-lactam resistance of penicillin-binding protein2x, 2b, and 1a of <i>Streptococcus pneumoniae</i> in clinical pneumococcal isolates.

Microbiology spectrum·2026

Same author

Magnetic Resonance Spectroscopy Deep Learning with Magnetic Resonance Background Generator Enables In Vivo Metabolite Quantification of Hepatic Encephalopathy.

IEEE transactions on bio-medical engineering·2026

Same author

PolyMamba-Net: a lightweight and boundary-aware network for real-time polyp segmentation in colonoscopy.

Frontiers in medicine·2026

Same author

Real-Time Stress Visualization of Hydrogels Enabled by Supramolecularly Switched Stretch-Induced Phase Separation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

Triglyceride-glucose index and systemic immune-inflammation index are associated with left ventricular hypertrophy in type 2 diabetes mellitus patients.

BMC endocrine disorders·2026

Same author

A Reproducible Multichannel Synchronous Rapid Phosphopeptide Enrichment Strategy Enabled by Anisotropic Porous Chitosan-Based Arrays.

Analytical chemistry·2026

Same journal

Reprocessable Disulfide-Based Vitrimers with Adhesive Properties.

Macromolecular rapid communications·2026

Same journal

Micro- and Nanopatterning of Highly Conductive PEDOT Thin Films.

Macromolecular rapid communications·2026

Same journal

From Molecular Structure to Macroscopic Performance: Insights into Polycarbosilane Curing.

Macromolecular rapid communications·2026

Same journal

High-Yield Synthesis of Molecular Bottlebrushes With Block Copolymer Side Chains by the Copper Superoxido Complex Enabled ATRP via a Grafting-From Approach.

Macromolecular rapid communications·2026

Same journal

Chemically and Mechanically Recyclable Polyolefins Incorporating Covalent Adaptable Networks.

Macromolecular rapid communications·2026

Same journal

Designing Thermally Stable DNA Hydrogels via Entropically-Driven Acridine Intercalation.

Macromolecular rapid communications·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 8, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Dimensionally Stable and Mechanically Adaptive Polyelectrolyte Hydrogel.

Chen Qian¹, Taka-Aki Asoh¹, Hiroshi Uyama¹

¹Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Macromolecular Rapid Communications

|September 22, 2020

Summary

This summary is machine-generated.

Mechanically adaptive hydrogels now maintain dimensional stability. Introducing an opposite swelling mechanism in alginate-polystyrene sulfonate (Alg-PSS) hydrogels prevents volume changes during mechanical adaptation.

Keywords:

alginate calcium ion dimensional stability mechanical adaptivity polyelectrolyte

More Related Videos

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

Related Experiment Videos

Last Updated: Dec 8, 2025

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Microwave-assisted Functionalization of Polyethylene glycol and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Preparation of DNA-crosslinked Polyacrylamide Hydrogels

Published on: August 27, 2014

Area of Science:

Materials Science
Polymer Chemistry
Biomaterials Engineering

Background:

Mechanically adaptive hydrogels offer environmental responsiveness.
Swelling and shrinkage during mechanical changes limit their practical applications.
Alginate-based polyelectrolyte hydrogels are promising for adaptive materials.

Purpose of the Study:

To develop mechanically adaptive hydrogels with high dimensional stability.
To overcome the swelling/shrinkage issue in adaptive hydrogels.
To explore applications in artificial valves and soft robotics.

Main Methods:

Constructed dually crosslinked alginate-polystyrene sulfonate (Alg-PSS) hydrogels.
Utilized copolymerization of alginate-methacrylate (Alg-MA) and sodium p-styrene sulfonate (NaSS).
Incorporated Ca2+ crosslinking and leveraged Na+ ion disruption for mechanical adaptation.

Main Results:

Achieved significant mechanical property changes with suppressed volume variation.
Demonstrated a tensile modulus drop from 191.3 kPa to 15.1 kPa in optimized Alg-PSS hydrogels.
Observed a negligible volume increase ratio of only 0.6% in 2.0 mol L-1 NaCl solution.

Conclusions:

Developed mechanically adaptive Alg-PSS hydrogels with excellent dimensional stability.
The PSS chains' coil-globule transition in NaCl suppresses swelling during softening.
These hydrogels are suitable for applications requiring invariable volume and mechanical responsiveness.